Dr. Manuel Tisminetzky

Dr. Manuel Tisminetzky

Clinical Research Fellow, Chief Fellow, 2021-2022

Medical/Professional Qualifications

Interdepartmental Division of Critical Care Medicine, University of Toronto

Dr. Tisminetzky was born in Buenos Aires, Argentina. He obtained his medical degree at Instituto Universitario Escuela de Medicina del Hospital Italiano in 2012. He then went on to complete his critical care residency at Hospital Italiano de Buenos Aires. In 2017, he was appointed chief of residents and clinical associate until he came to Toronto in 2019. His training in Quality Improvement and Patient Safety includes a Certificate Course from the Centre for Quality Improvement and Patient Safety (CQuIPS), and in 2023, he completed an MSc in Quality Improvement and Patient Safety at the Institute of Health Policy, Management, and Evaluation, of the University of Toronto.

Areas of Interest/Research
Mechanical Ventilation, ARDS, ECLS, &
Patient Safety


  1. Tisminetzky M, Ferreyro BL, Sklar MC, Chen L, Keshavjee S, Cypel M, Fan E, Ferguson ND, Brochard L, Douflé G, Del Sorbo L. Low-Flow Inflation Pressure-Time Curve to Identify Airway Opening Pressure in a Patient Receiving Venovenous Extracorporeal Membrane Oxygenation. Am J Respir Crit Care Med. 2023 Jun 1;207(11):e97-e98. doi: 10.1164/rccm.202204-0647IM. PMID: 36693031.
  2. Del Sorbo L, Tisminetzky M, Chen L, Brochard L, Arellano D, Brito R, Diaz JC, Cornejo R. Association of lung recruitment and change in recruitment-to-inflation ratio from supine to prone position in acute respiratory distress syndrome. Crit Care. 2023 Apr 13;27(1):140. doi: 10.1186/s13054-023-04428-3. PMID: 37055792; PMCID: PMC10098997.
  3. Tisminetzky M, Ferreyro BL, Fan E. Extracorporeal Membrane Oxygenation in COVID-19. Crit Care Clin. 2022 Jul;38(3):535-552. doi: 10.1016/j.ccc.2022.01.004. Epub 2022 Jan 10. PMID: 35667742; PMCID: PMC8743573.
  4. Tisminetzky M, Ferreyro BL, Frutos-Vivar F, Esteban A, Rios F, Thille AW, Raymondos K, Del Sorbo L, Penuelas O, Fan E. Decline in ventilatory ratio as a predictor of mortality in adults with acute respiratory distress syndrome receiving prone positioning. Respiratory CareSeptember 2022,  67 (9) 1067-1074; DOI: https://doi.org/10.4187/respcare.09783
  5. Dianti J, Tisminetzky M, Ferreyro BL, Englesakis M, Del Sorbo L, Sud S, Talmor D, Ball L, Meade M, Hodgson C, Beitler JR, Sahetya S, Nichol A, Fan E, Rochwerg B, Brochard L, Slutsky AS, Ferguson ND, Serpa Neto A, Adhikari NKJ, Angriman F, Goligher EC. Association of Positive End-Expiratory Pressure and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis. Am J Respir Crit Care Med. 2022 Jun 1;205(11):1300-1310. doi: 10.1164/rccm.202108-1972OC. PMID: 35180042.
  6. Tisminetzky M, Dianti J, Ferreyro BL, Angriman F, Del Sorbo L, Sud S, Talmor D, Fan E, Ferguson ND, Serpa Neto A, Adhikari NKJ, Goligher EC. Association of different positive end-expiratory pressure selection strategies with all-cause mortality in adult patients with acute respiratory distress syndrome. Syst Rev. 2021 Aug 12;10(1):225. doi: 10.1186/s13643-021-01766-7. PMID: 34384488; PMCID: PMC8357961.
  7. Dianti J, Matelski J, Tisminetzky M, Walkey AJ, Munshi L, Del Sorbo L, Fan E, Costa EL, Hodgson CL, Brochard L, Goligher EC. Comparing the Effects of Tidal Volume, Driving Pressure, and Mechanical Power on Mortality in Trials of Lung-Protective Mechanical Ventilation. Respir Care. 2021 Feb;66(2):221-227. doi: 10.4187/respcare.07876. Epub 2020 Aug 25. PMID: 32843513.
  8. Ortega F, Carboni Bisso I, Fernandez Ceballos I, Montserrat Rivera A, Tisminetzky M, Dianti J, San Román E, Villarroel S, Di Stefano S, Las Heras M. Utilización de membrana de circulación extracorpórea en síndrome de leak capilar idiopático: reporte de un caso [Use of Extracorporeal Membrane Oxygenation in idiopathic capillary leak syndrome: a case report]. Rev Fac Cien Med Univ Nac Cordoba. 2020 Aug 21;77(3):208-210. Spanish. doi: 10.31053/1853.0605.v77.n3.26960. PMID: 32991115.
  9. Heras MJL, Dianti J, Tisminetzky M, Svetliza G, Giannasi SE, Roman ES. Cryoprobe biopsy for the diagnosis of acute hypoxemic respiratory failure of undetermined origin. J Intensive Care Soc. 2020 May;21(2):119-123. doi: 10.1177/1751143719847323. Epub 2019 May 7. PMID: 32489407; PMCID: PMC7238481.

Honours and Awards
UHN Critical Care Medicine Quality Improvement Grant (2021)

Personal Interests
Football, rugby, skiing

manuel.tisminetzky@uhn.ca, manueltismi@gmail.com



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