Attending physician, Toronto Western Hospital
PhD, UCNS, FRCPC (Critical Care Medicine and Internal Medicine), MRCPUK, MBChB, BSc.
Department of Medicine, Interdepartmental Division of Critical Care, University of Toronto
Dr. McCredie received her undergraduate degree in medical sciences at the University of St. Andrews; her medical degree from University of Manchester; and her internal medicine training at University of Manchester. Dr. McCredie moved to Canada in 2009 to complete a critical care fellowship and then a further sub-specialized neurocritical care fellowship, both at the University of Toronto. Her certifications include internal medicine from Royal College of Physicians U.K., internal medicine and critical care medicine from the Royal College of Physicians and Surgeons of Canada, and neurocritical care medicine from the United Council for Neurological Subspecialties in the United States. She received additional doctoral research training in clinical epidemiology at the University of Toronto. Her research focuses on clinical epidemiology methods to examine the relationship between process of care, structure and outcome for critically ill patients with acute brain injury. Her research also focuses on evaluating pathophysiologic mechanisms contributing to secondary brain injury processes during critical illness, looking specifically at the role of blood transfusions in traumatic brain injury and the effects on cerebral tissue oxygenation. She has also published on topics related to the withdrawal of life-sustaining therapies in severe traumatic brain injury, airway management strategies for acutely brain injured patients, and statistical modelling methods.
Area of academic focus
Clinical epidemiology methods to examine the relationship between process of care, structure and outcome for critically ill patients with acute brain injury.
Pathophysiologic mechanisms contributing to secondary brain injury processes during critical illness
Withdrawal of life-sustaining therapies in severe traumatic brain injury,
Airway management strategies for acutely brain injured patients
Statistical modelling methods.
Honours and Awards
2016 Canadian Critical Care Trials Group Young Investigator Retreat Award
2016 Gillian Hawker Best PhD Award, Clinical Epidemiology & Health Care Research, Institute of Health Policy, Management and Evaluation Annual Research Day, University of Toronto
2014 The Garner King Award Best Scientific Poster, Canadian Critical Care Forum
Link to Pubmed
Most Significant Publications
- McCredie VA, Ferguson ND, Pinto RL, Adhikari NKJ, Fowler RA, Chapman MG, Baker AJ, Cook DJ, Meade MO, Scales DC. Airway management strategies for brain-injured patients meeting standard criteria to consider extubation: An observational cohort study. Ann Am Thorac Soc. 2017 Jan;14(1):85-93. (PMID: 27870576) (FIRST AUTHOR)
- McCredie VA, Piva S, Rigamonti A, Airton L, Hare G., Baker A. The Impact of Red Blood Cell Transfusion on Cerebral Tissue Oxygen Saturation in Severe Traumatic Brain Injury. Neurocritical Care. 2017 Apr;26(2): 247-255. (PMID: 27757915) (FIRST AUTHOR)
- McCredie VA, Alali A, Scales DC, Adhikari N, Rubenfeld GR, Cuthbertson B, Nathens AB. Effect of early versus late tracheostomy or prolonged intubation in critically ill patients with acute brain injury: a systematic review and meta-analysis. Neurocritical Care. 2017 Feb;26(1):14-25 (PMID: 27601069) (FIRST AUTHOR)
- McCredie VA, Alali A, Xiong W, Cuthbertson B, Rubenfeld G, Scales DC, Nathens AB. Timing of withdrawal of life support in patients with severe traumatic brain injury does not explain variations in mortality between trauma centres. J Trauma Acute Care Surg. 2016 Mar;80(3):484-91 (PMID: 26595711) (FIRST AUTHOR)
- Zakrison TL, Austin PC, McCredie VA. A Systematic Review of Propensity Score Methods in the Acute Care Surgery Literature: Avoiding the Pitfalls and Proposing a Set of Reporting Guidelines. Eur J Trauma Emerg Surg. 2017 Mar 24 (PMID: 28342097) (SENIOR AUTHOR)