Dr. Ewan Goligher

Toronto General Hospital

Academic Rank
Assistant Professor

Position Title
Clinician-Scientist

Medical/Professional Qualifications
MD, PhD, FRCPC

Affiliations
Department of Medicine

Biography
Ewan Goligher studied medicine at the University of British Columbia and trained in internal medicine and critical care medicine at the University of Toronto. Upon completion of his clinical training, he undertook Doctoral studies in physiology at the University of Toronto, completing his PhD in 2016. His research aims to delineate mechanisms of injury from mechanical ventilation with a view to prevention and treatment in order to improve outcomes for patients with acute respiratory failure around the globe.

Area of Academic Focus
Mechanisms and outcomes of patient-ventilator interaction; respiratory muscle injury from mechanical ventilation and its impact on patient outcomes

Honours and Awards
2015                Best Oral Abstract (Physiology), Art Slutsky Research Day, Interdepartmental Division of Critical Care, University of Toronto
2014                Abstract Scholarship Award, American Thoracic Society
2014                Best Oral Abstract, Resident Research Day, Interdepartmental Division of Critical Care, University of Toronto
2012                Best Oral Abstract, Resident Research Day, Interdepartmental Division of Critical Care, University of Toronto
2009                Best Clinical Research Poster, Critical Care Canada Forum
2009                Outstanding Housestaff Award, University Health Network, Toronto
2008                Outstanding Housestaff Award, Mount Sinai Hospital, Toronto

Publications
Link to PubMed

Most Significant Publications

1. Goligher EC, Ferguson ND, Brochard LJ. Clinical Challenges in Mechanical Ventilation. Lancet 2016;387:1856-1866.
2. Goligher EC, Fan E, Herridge MS, Murray A, Vorona S, Brace D, Rittayamai N, Lanys A, Tomlinson G, Singh JM, Bolz SS, Rubenfeld GD, Kavanagh BP, Brochard LJ, Ferguson ND. Evolution of Diaphragm Thickness During Mechanical Ventilation: Impact of Inspiratory Effort. Am J Respir Crit Care Med. 2015;192(9):1080-8.
3. Goligher EC, Kavanagh BP, Rubenfeld GD, Ferguson ND. Physiologic Responsiveness Should Guide Entry into Randomized Controlled Trials. Am J Respir Crit Care Med. 2015;192(12):1416-9.
4. Goligher EC, Laghi F, Detsky ME, Farias P, Murray A, Brace D, Brochard LJ, Sebastien-Bolz S, Rubenfeld GD, Kavanagh BP, Ferguson ND. Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med. 2015;41(4):642-9. [Erratum published]
5. Goligher EC, Kavanagh BP, Rubenfeld GD, Adhikari NK, Pinto R, Fan E, Brochard LJ, Granton JT, Mercat A, Marie Richard JC, Chretien JM, Jones GL, Cook DJ, Stewart TE, Slutsky AS, Meade MO, Ferguson ND. Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med. 2014;190(1):70-6.

Contact
E-mail: ewan.goligher@uhn.ca